The computational biology laboratory of the Sapienza University in Rome is a multidisciplinary Unit established in 2001 composed by physicists, computer scientists, engineers, chemists, pharmaceutical chemists, biotechnologists and biologists. The head of the group, Anna Tramontano, has been working in the area of computational biology and bioinformatics (ante literam) since 1980 in the USA and Europe, in both academic and industrial setups.
Our group research activities are devoted to the computational analysis of biological data, to the development and improvement of methods for the analysis of genomes and proteomes and to the applications of methods to problems of biomedical interest. The group is involved in many world-wide initiatives aimed at analysing post-genomic biological data in order to improve our understanding of life at a molecular level.
Our recent research interests can be divided, with some overlap, into two main directions: development and/or improvements of computational biology methods and their application to the study of problems of biomedical interest.
Other relevant activities of the group concern the organization of the world-wide CASP (Critical Assessment of Techniques for Protein Structure Prediction) experiment, the involvement in the recently established Center for Life Nano Science funded by the Italian Institute of Technology and the participation to the Italian Epigenomics Flagship Project, where we are co-coordinating the Bioinformatics efforts.